Welcome to the next frontier of bone regeneration

SmartBone® is produced by combining natural mineral bone structures with bioresorbable polymers and collagen fragments. This new concept of biomaterial assembly allows the patient’s cells to grow quickly and efficiently into the bone substitute while the biopolymers degrade, providing perfect integration and osteogenesis.

The microstructure of SmartBone®’s composite matrix strongly resembles the human bone in terms of open, interconnected and mid-sized porosity. Indeed, it mimics the characteristics of a healthy human bone: high biocompatibility, adequate open porosity, high mechanical performance, hydrophilicity.

Thanks to its microcomposition, SmartBone® quickly reaches an av. 38%w/w blood swelling ratio, thereby sparking the chemical signaling cascade that  finally induces a robust osteointegration.

After 2.5 years the graft has been completely replaced and the osteogenesis has formed a lamellar bone with cement lines; there is evidence of a great amount of osteocytes inside the lacunae and of a good angiogenesis.

SmartBone®, combined with the native bone, forms an osteoinductive system.